Former Miss Florida and the wife of “Tarzan” actor Ron Ely was stabbed to death by their 30-year-old son, who was fatally shot by sheriff’s deputies, shortly after.Police arrived at the scene and found 62-year-old Lundeen Ely dead with multiple stab wounds shortly after 8 p.m., Tuesday evening.The deceased suspect is identified as Cameron Ely.After killing his mother, he is heard in a chilling 911 call, alleging that his father was responsible for the attack.Authorities confirmed Ron Ely was home during the gruesome incident but could not communicate with officers because of his compromised speech from a medical condition.The 81-year-old was not injured but taken to a local hospital for evaluation.He is known for playing the title character on the NBC series “Tarzan,” which ran from 1966 to 1968.He was also the host of the Miss America pageant in 1980 and 1981, where he met his wife.Before marrying Ron, Valerie competed in the Miss Florida competition in 1981, representing the city of Miami.She went on to compete at the Miss USA beauty pageant later that year but did not win.The couple had three children and were married for about 35 years.Besides their son Cameron who reportedly lived with his parents, the couple shared two daughters, Kirsten and Kaitland, 32.Kirsten, a social media influencer, referred to her mother as her best friend in a 2010 blog post. The family has not spoken out at this time.It is unclear what events led to the tragedy, or whether Cameron committed suicide by cop.An autopsy for both Valerie and Cameron is pending.
LATEST STORIES Steam emission over Taal’s main crater ‘steady’ for past 24 hours Phivolcs records 2 ‘discrete weak ash explosions’ at Taal Volcano UAAP volleyball: FEU holds off UP, joins Ateneo at fourth Lights inside SMX hall flicker as Duterte rants vs Ayala, Pangilinan anew It’s too early to present Duterte’s ‘legacy’ – Lacson Rommel Abella emerged a winner in his head coaching debut in the Philippine Superliga, but the multi-titled mentor was not overly satisfied with how his new team Foton performed to open the 2018 season.The Tornadoes turned back the Generika-Ayala Life Savers, 25-19, 22-25, 25-16, 25-22, but Abella wants to more from his team in the coming games.ADVERTISEMENT “If I’m going to rate our performance earlier, we’re just 60 to 70 percent. Like I said, hopefully, we improve on our mistakes,” he said on Saturday at the start of the Grand Prix tournament at Ynares Sports Arena in Pasig.The Tornadoes leaned on their hard-hitting trio of Brooke Kranda, Elizabeth Wendel and Dindin Santiago-Manabat, who combined for 46 points.FEATURED STORIESSPORTSTim Cone, Ginebra set their sights on elusive All-Filipino crownSPORTSGinebra beats Meralco again to capture PBA Governors’ Cup titleSPORTSAfter winning title, time for LA Tenorio to give back to Batangas folkKranda, a former Michigan State University star in the US NCAA, scored a game-high 21 points in her professional debut while Manabat and Canadian import Wendel had 14 and 11 points, respectively.Abella is pleased to see Manabat back in action after suffering an ACL injury last conference, but expects more from his imports particularly on the offensive end in the coming games. MOST READ Nueva Ecija warehouse making fake cigarettes raided, 29 Chinese workers nabbed View comments “Actually, we’re expecting a little more. But since it’s only their first game here in the Philippines, their performance is acceptable, but hopefully, they can provide us with more offensive power in our next game.” UK plans Brexit celebrations but warns businesses may suffer Phivolcs records 2 ‘discrete weak ash explosions’ at Taal Volcano Sea turtle trapped in net freed in Legazpi City Don’t miss out on the latest news and information. Carpio hits red carpet treatment for China Coast Guard PLAY LIST 02:14Carpio hits red carpet treatment for China Coast Guard02:56NCRPO pledges to donate P3.5 million to victims of Taal eruption00:56Heavy rain brings some relief in Australia02:37Calm moments allow Taal folks some respite03:23Negosyo sa Tagaytay City, bagsak sa pag-aalboroto ng Bulkang Taal01:13Christian Standhardinger wins PBA Best Player award Sports Related Videospowered by AdSparcRead Next GALLERY: Barangay Ginebra back as PBA Governors’ Cup kings
By BEN HARRISSydney Rebels continued their dominance in the mixed open division at the National Touch League when they claimed their fifth consecutive crown.With the quest of the ‘#fivepeat’ firmly set in their minds, the Rebels were simply untouchable on finals day of the NTL.They hammered Defence Warriors 16-5 in the quarter-final before fighting tooth and nail to knock off Sydney Scorpions 9-5 in the semi-final.In the final, the Rebels played their archrivals Brisbane City Cobras for the third consecutive year.The Cobras were looking for third time lucky but they stumbled out of the blocks and despite fighting back, they went down 6-4.Rebels co-captain Kirstie Wakely has been involved in all of her team’s victories and said this one was the sweetest.“It’s pretty awesome, I am so pleased. Our team probably played the best they’ve played for the entire tournament, so I’m really happy with it,” Wakely said.The Rebels scored three touchdowns in the first nine minutes to set the tempo of the game.Credit to the Queensland team, they fought back to make it 3-2 just before half-time.But Rebels’ co-captain Roy Prasad scored his second of the half to give his team a 4-2 lead at the break.Midway through the second half the next score was added and it went to the Cobras.But the Rebels’ reply was swift as they scored less than 90 seconds later.A superb flick pass from Cobras’ Aiden Beiers to Tasi Cordtz made the scores 6-5 with seven minutes to go.Both sides were denied more touchdowns and it wasn’t until the 37th minute the Rebels put the nail in the Cobras’ coffin courtesy of an Ashleigh Werner touchdown.“Cobras are always tough. Our game plan is we don’t want to slip up, make no mistakes and if we stick to that, hopefully we can come away with a win,” Wakely said.The co-captain credited her team’s attitude, which has played a big part in their success for the past five years.“They are such a positive and tight crew and I think that helps us to bond in the end,” she said.Wakely and Prasad were named the players of the final.SYDNEY REBELS 6 (Roy Prasad 2, Kirstie Wakely, Amy Lugg, Ashleigh Werner, Jamie Chan touchdowns) def BRISBANE CITY COBRAS 4 (Allan Shine, Jordan Lovejoy, Kenneth Adams, Tasi Cordtz touchdowns).Related LinksMixed open final
TagsTransfersAbout the authorPaul VegasShare the loveHave your say Arsenal, Juventus alerted as Avdijaj rejects Willem II offerby Paul Vegas10 months agoSend to a friendShare the loveDonis Avdijaj plans to leave Willem II at the end of the season.Off contract in June, Avdijaj has refused to consider talks about a new deal with Willem, says Soccernews.nl.Instead, the attacker is ready to leave in June – a decision which has attracted the interest of two of Europe’s biggest clubs.Arsenal and Juventus are both eyeing Avdijaj for a Bosman transfer.Avdijaj, 22, joined Willem II in the summer from Schalke, signing a 12 month deal.
The women’s volleyball team finished big at home this weekend, upsetting No. 12 Michigan and defeating Michigan State en route to an NCAA Tournament berth.A 3-0 sweep of Michigan earned the Buckeyes their second win over a ranked opponent this season. OSU won the three sets 25-20, 25-22 and 25-22.The Buckeyes had the edge over Michigan in hitting. They had four ace serves, two of which came from the hands of Kelli Barhorst. Several players shared match-highs against Michigan, including Katie Dull’s 16.5 points and three blocks. The Buckeyes entered their last regular season match at St. John Arena on Saturday evening.With the momentum from blowing past Michigan and the Big Ten tournament on the horizon, the Buckeyes were on the attack.The Buckeyes took an early 17-12 lead in the first set but got stuck behind a five-point run by Michigan State. Holding a 24-20 lead, the Buckeyes took the set off a Michigan State error. In the second set, senior Ashley Hughes began to rack up the 25 assists, five blocks, five kills and four digs she earned across the match. Dull added to her match-highs on the weekend with 17.5 points, 13 kills, and a career-tying three solo blocks. The Buckeyes added another 3-0 sweep to their weekend, winning all three sets against MSU, 25-21, 25-20 and 25-15. Following two big wins to close the season, seniors Kristen Dozier, Ashley Hughes and Chelsea Noble were joined by their families on the court. Dozier and Hughes played for the Buckeyes for four seasons, and Noble has contributed for two seasons. Each player was recognized for her career achievements and received her own framed jersey. In their final singing of “Carmen Ohio” in St. John Arena, the seniors joined arms with their families to remember every match played on their home court. The Buckeyes finished the season 23-9 overall and 12-8 in Big Ten play. The Buckeyes finished tied for fourth in the Big Ten with Michigan. OSU concluded its perfect weekend by earning an NCAA Tournament berth Sunday. The Bucks will host Cincinnati in a first-round matchup Friday at St. John Arena. If OSU beats the Bearcats, it will advance to face the winner of Lipscomb-California at home Saturday.
There was a reading by Emanuele Piccardo, architecture critic and filmaker, from the books:Paolo Soleri, Arcology: The city in the image of man, MIT Press 1969Reyner Banham, Scenes in America Deserta, Gibs M. Smith Inc, 1982There were interviews via Skype with Giuliano Gresleri, architecture historian, director of the magazine Parametro that published the work of Soleri in the 1976; Matteo Di Michele [photo].Also Antonino Saggio, professor at the School of Architecture University La Sapienza-Rome, William Menkind editor The Architect’s Newspaper.There also was a projection of “P.Soleri 38’38””, Emanuele’s interview realized in Cosanti in june 2006. October 9, 2013Emanuele Piccardo organized a memorial event on September 25. in Genova, Italy to celebrate Paolo Soleri in Emanuele’s home town Genova with the Italians that met Paolo in these years: Luigi Spinelli, Matteo Di Michele, Antonino Saggio, Piergiorgio Tosoni. In this occasion he showed his documentary on Soleri and the participants read the frames of the book Arcology.The photos arrived this morning, of the event “Paolo Soleri, ricordo di un architetto visionario” at the Order of Architects of Genova.[photos and text courtesy Emanuele Piccardo]
By Robert Ross, Casey ResearchThis week, President Obama released his $3.8-trillion budget for fiscal year 2013. The plan calls for new taxes on the wealthy, a restructuring of the tax code, and short-term infrastructure spending aimed at boosting the economy (albeit artificially).Also included in the budget are limitations on subsidies for oil and gas companies, an end to the Bush tax cuts, and a proposal to raise taxes on dividends, which could be as high as 39.6% for households making over $250,000 per year.Although Senate Minority Leader Mitch McConnell (R-KY) dismissed the proposal as “a campaign document,” the White House claims the measure would generate $206 billion in revenue over 10 years.One of the most interesting aspects of the plan is the inclusion of the Buffett Rule as a replacement for the alternative-minimum tax (AMT).The AMT was originally implemented to ensure that high-income Americans paid their taxes. But, alas, the geniuses in Washington “forgot” to index the AMT for inflation, rendering it useless and unintentionally ensnaring an increasing number of middle-class taxpayers into a system meant for the wealthiest of Americans.Unintended consequences abound, but I digress…The “Buffett Rule,” named after famed investor Warren Buffett, would require those who earn more than $1 million per year to pay a tax rate of at least 30% and prevent them from claiming deductions to push down their tax rates.Buffett, who penned a New York Times op-ed in August of last year espousing the need for an overhaul of the tax code for America’s top earners, appears to have caught the ear of President Obama.(Click on image to enlarge)The message of the op-ed was clear: Mr. Buffett, who paid nearly $7 million in income tax last year, wants to pay more.But will he actually sacrifice anything? It’s hard to say, as some of these new taxes will directly benefit Buffett.Additional tax dollars in the government’s coffers could help Buffett even more. Who can forget the Oracle of Omaha’s opportunistic investment in Goldman Sachs (NYSE: GS) in the wake of the Lehman Brothers collapse (where he made nearly $1 billion on the assumption that the government would bail it out)? Buffett has indicated that his next acquisition could be Exelon (NYSE: EXC), General Dynamics Corp (NYSE: GD), or Archer Daniels Midland (NYSE: ADM), all of which are heavily connected to government contracts and would benefit from increased government spending.Exelon is directly tied to the Obama administration: Rahm Emanuel and David Axelrod act as consultants, two top Exelon advisors are Obama fundraisers, and the company lobbies heavily for more greenhouse-gas restraints to drive demand for its nuclear power.General Dynamics, the world’s fifth-largest defense company, generated 72% of revenue from the Department of Defense in 2011, and was the number-four government contractor for fiscal year 2011.Last but certainly not least, ADM, one of the world’s largest processor of agricultural commodities, profits not only from ethanol subsidies but from corn syrup and export subsidies as well.Although no one can be sure of Buffett’s motives, it would be naïve to believe that someone as intelligent as Buffett has not considered the benefits of pushing through this tax structure. Higher taxes are always problems for entrepreneurs and regular people in the economy. However, they’re often beneficial to the well-connected, who receive government bailouts and favors. And with Buffett even on the president’s lips, he is becoming more connected to the power mechanism in D.C. every day. With many of Berkshire’s companies, your loss as a taxpayer will be their gains.[Warren Buffett is right to be concerned about the US federal government’s debt levels – it is the country’s biggest security threat by far. And it’s getting worse. But you can protect yourself and your wealth, if you have accurate information on the trends and how to play them. Start learning about it now.]
Developing drugs to treat disease is never easy. But recent research into a relatively unknown area of science provides us with a wealth of new opportunities for drug discovery in the areas of cancer, cardiovascular disease, diabetes, neurodegenerative disorders, and inflammation, among others. Throughout most of history, new drugs have been discovered through a process of trial and error or simply through dumb luck. Think of Alexander Fleming who discovered penicillin in 1928 (actually he rediscovered it, but that’s a story for another day) when some bacterial cultures he was working with became contaminated by a blue-green mold, and he noticed that colonies of bacteria adjacent to the mold were being dissolved. Since neither trial and error nor reliance on luck make for a particularly strong business model, biotech and pharma companies have started to adopt a new method of drug development called rational drug design, wherein molecules and compounds are specifically designed or chosen to attack a particular target. Today, the vast majority of molecular drug targets are proteins (and a small percentage are nucleic acids). According to biologist R.A. Sabbadini, writing in the British Journal of Cancer a few years ago: “The focus on proteins was a natural consequence of our evolving understanding of biochemistry, which allowed researchers to identify potential protein targets involved in key metabolic and signaling pathways. Some of the first drugs developed by the rational drug design approach to the scientific method came after the discovery of key enzymes, receptors and ion channels [all proteins] as they emerged in the basic science literature. One can argue that target identification now is driven by the technological developments of proteomics and genomics, both of which reflect our persistent ‘protein-centric’ view of drug discovery.” Long story short, it made sense for drug developers to target proteins, because proteins are known to regulate many normal cellular functions – like cell division, cell migration, and cell death – but over time they could become dysregulated and cause disease. So scientists focused on developing drugs that neutralized these disease-causing proteins. While proteins will continue to play a big role in drug development for the foreseeable future, the emerging field of “lipidomics” provides both a wealth of new therapeutic targets and distinct advantages over protein-centric drug discovery. Like the other “-omic” disciplines (i.e., genomics, proteomics, etc.), lipidomics refers to all the members of the lipid family of compounds. Scientists are trying to develop methods to analyze all the lipids of cells. This isn’t easy, considering that lipids vary considerably in structure. Moreover, depending on whose estimate you use, the number of different molecular species could be in the tens of thousands to hundreds of thousands. In fact, of the four basic types of molecules that are the major players in biological systems (including the human body) – i.e., nucleic acids, carbohydrates, proteins, and lipids – lipids stand out for their sheer number of distinct molecular species. The study of lipidomics is further complicated by the fact that, unlike genomics and proteomics, we can’t predict the number of individual lipid molecules present in an organism. Thus, current technologies are still unable to map lipidomes. But scientists are making progress thanks to technological advancements, particularly those in mass spectrometry. We used to think of lipids as just the building blocks of cell membranes and fuel-storage molecules for cellular maintenance. Through the study of lipidomics, however, scientists have discovered that lipids play key roles in all areas of cell biology as signaling and regulatory molecules – in other words, they can be what’s known as bioactive molecules. The notion of “bioactive lipids,” which is broadly defined as changes in lipid levels that result in functional consequences, has started to gain traction over the past couple of decades; medical researchers now recognize that these bioactive lipids play key roles in many diseases and represent new targets for rational drug design. For example, the bioactive lipid lysophosphatidic acid (LPA) plays a key role in regulating nerve injury and pain. If you can develop a drug that neutralizes LPA, you can block the signals to the brain and ease the pain of a patient who has been injured. There are an estimated 1,000+ bioactive lipids that play key roles in all kinds of diseases, providing a gold mine of potential targets for drug makers. What’s more, bioactive lipids are much smaller and simpler molecules than proteins and generally don’t vary from species to species. Thus, the data from animal models tends to be much more predictive of success in the clinical setting than with protein-targeted drug development programs. There are already well-known drugs that target lipid metabolic and signaling pathways, including the cholesterol-lowering statins. But so far, due to their extremely small size and the fact that they are not water soluble, drug companies have had a problem targeting bioactive lipids directly – until now. In a recent issue of Casey Extraordinary Technology, we recommended a micro-cap company that is poised to emerge as the leader in lipid-based therapeutics, thanks to its novel platform technology that can develop drugs to directly target any of these molecules. That’s exciting enough, but to add icing on the cake, the company has already developed a pipeline of drugs in clinical trials. The firm’s lead drug candidate (currently in Phase II trials) could generate annual peak sales many times that of its current market capitalization. If this piques your interest, give Casey Extraordinary Technology a risk-free test drive. When you sign up, you’ll have access to our entire current portfolio of investments and our archives. If you’re not completed satisfied with the product, you can cancel your subscription within 90 days of signing up for a full refund. It’s that simple. Bits & Bytes How a Supercomputer Unlocked HIV (Gizmodo) Part of the reason why HIV is so difficult to treat is due to the structure of its viral casing, or capsid, which is critically important for the virus’ replication, but the precise structure of which has remained a mystery. Until now. Thanks to the efforts of researchers from the University of Illinois and number crunching from a supercomputer, the capsid’s structure has been revealed. This discovery could lead to an entirely new suite of treatment alternatives to help in the fight against HIV. Solving a 3.5 Billion-Year-Old Mystery (University of South Florida) If you ask a biologist or organic chemist what the necessary elements for life are here on earth, he or she will probably reply “CHON,” shorthand for carbon, hydrogen, oxygen, and nitrogen. But then the answer will quickly be qualified with, “And you need sulfur and phosphorus too.” Phosphorus is one of the three elements that crops require in large amounts in order to grow, and it was an essential component for creating the earliest life forms on Earth. New research from a team of scientists led by a University of South Florida astrobiologist now shows that phosphorus was carried here on meteorites. According to USF Assistant Professor of geology Matthew Pasek, “Meteorite phosphorus may have been a fuel that provided the energy and phosphorus necessary for the onset of life.” Hackers Break into Any iPhone Using a Malicious Charger (ExtremeTech) Security researchers from the Georgia Institute of Technology have built a malicious USB charger, called Mactans, which can compromise any current generation iOS device in less than a minute. Mactans will be demonstrated at the Black Hat 2013 conference in July. Apple has been informed of the vulnerability, but it presumably has not been fixed yet since the researchers refuse to give out exact details until the conference.